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About Buprenorphine

Buprenorphine is an Opioid drug sold under the brand Subutex. It is an essential element used in the treatment plan for opioid use disorder (OUD) that is used in combination with (social or behavioral therapy and counseling).

It is a partial opioid agonist used to treat Opioid Use Disorder (OUD) and severe pain. This medication also helps in reducing Opioid cravings and withdrawal symptoms.

It is used in medication assessment treatment (MAT) to help people quit their addiction to Opioid medications such as pain relievers like Morphine.

It also reduces depression symptoms and decreases the risk of suicidal thoughts. When taken at analgesic doses, buprenorphine is 20 – 50 times more potent than morphine.

It offers several benefits to people with opioid dependency and addiction and for those who do not prefer treatment in a methadone clinic or is less convenient for them.

How Does Buprenorphine Work?

Buprenorphine works by binding to several opioid receptors of the brain and attaches to it more strongly than any other opioid medications.

It helps to reduce feelings of pain by interrupting the way nerves signal the pain between the brain and the body.

It eliminates the effects of other opioid medications, reduces the negative effects of withdrawals, and prevents the harm associated with opioid use.

This medication starts working within 1 – 2 hours of using the medication, and it has a relatively rapid onset of action than Methadone.

Uses Of Buprenorphine

Opioid Use Disorder (OUD)

  • This medication helps people with opioid use disorder and alcohol addiction and reduces opioid cravings and withdrawal symptoms caused due to opioid overdose.
  • Being a synthetic opioid agonist, it is an essential part of the treatment plan for Opioid Use Disorder (OUD) that is combined with social and behavioral training and individual counseling to help with OUD and to provide a whole-person approach.

Buprenorphine treatment helps in –

  • Lowering the risk of opioid abuse
  • Diminishing Opioid dependency and addiction
  • Reducing opioid cravings and withdrawals
  • Increasing safety in case of overdose

Severe Pain

  • This medication is also used to treat and manage severe pain and provides instant relief from pain caused by Opioid withdrawal symptoms.

It offers various benefits to people with Opioid addiction and to those whose treatment in a methadone clinic is not preferred or sufficient and is less convenient for them.

Who Cannot Use Buprenorphine?

Most adults can use Buprenorphine on a doctor’s prescription, but people with certain health conditions are not recommended to use this medication even on a doctor’s prescription.

Do not use Buprenorphine if you have been suffering from any of these conditions –

  • Hypersensitivity
  • Seizures or fits
  • Low-blood pressure
  • Severe liver disease
  • Urination problems
  • Breathing problems
  • Severe heart disease
  • History of alcohol abuse
  • Stomach or bowel blockage
  • Used any narcotic drug in the last 4 days

Dose Of Buprenorphine

The dose depends on various factors such as age, health, and in-depth health assessment by a doctor. It is prescribed for short-term use because of its potential for abuse, misuse, and addiction.

Sublingual Tablets –

  • The recommended dose to be used after treatment, induction, and stabilization is 4 – 24 mg taken sublingually in a day.
  • The target dose of this medication is 16mg, which is taken in a day.
  • Do not exceed Buprenorphine doses to more than 24mg strength in a day.

You must take the doses as recommended by your doctor or a healthcare professional for safe use and effective Opioid Use Disorder (OUD) treatment.

Possible Side Effects Of Buprenorphine

Buprenorphine causes mild side effects that are not harmful, and it does not cause any serious health issues.

Some of the common and most noticeable side effects caused by Buprenorphine are given below –

  • Fever
  • Confusion
  • Headache
  • Cravings
  • Irritability
  • Nausea
  • Vomiting
  • Constipation
  • Muscle aches or cramps
  • Sleepiness and tiredness
  • Rashes and redness on skin

What To Prevent During This Treatment?

You must remember these preventative measures while using Buprenorphine for safe and effective treatment.

  • Do not combine this medication with any other CNS depressant medications, such as Benzodiazepines.
  • Avoid drinking alcohol during Buprenorphine treatment to prevent any severe withdrawal symptoms.
  • Monitor for any side effects if you are suffering from any liver-related issues.
  • Avoid using any illicit drugs, sedatives, or tranquilizers that cause drug interaction, leading to overdose and breathing problems.
  • Pregnant and breastfeeding womens should avoid using this medication, as the formula can pass through the baby and can be harmful.
  • Stop using Buprenorphine immediately if you experience any unusual allergic reaction to this medication.

Where To Buy Buprenorphine Online?

Buying Buprenorphine online is a challenging task because of the drug shortage and multiple restrictions on it due to U.S. Food and Drug Administration regulations.

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Final Words

If this medication is not used as prescribed by a doctor, it can be harmful, as it carries a risk of abuse, misuse, and dependence, but the risks are lower than those of Methadone.

Do not use Buprenorphine for a longer period of time; otherwise, you may develop dependency and get addicted to it. People who are not diagnosed with Opioid use Disorder (OUD) should not use this medication.

Avoid sharing this medication with older adults, and keep it out of reach of children. If your treatment has been completed, you must return the tablets to a pharmacy or a medical store to prevent any abuse, misuse, and dependence.

For further information, contact our customer support team to resolve your queries and doubts about any medicines and their uses.

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