Tramadol Description 

Tramadol is an opioid analgesic that is sold under the brand name Ultram, among others. This medication is used to treat and manage moderate to severe pain when all other non-opioid medications fail to work or are ineffective in the treatment. 

This medication is approved by FDA (food and drug administration) as it complies with its safe to use regulation. But in 2014, it was classified as a class IV substance. Doctors recommend using this medication only for a short-term treatment of pain for its safe use. 

This medication works directly on the opioid receptors in the central nervous system (CNS) of the brain to reduce the feeling of pain and response by interrupting the way between the brain and spinal cord.

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Strength And Forms Of Tramadol 

Tramadol comes in two forms such as immediate-release, and extended-release tablets. Immediate-release tablets start working immediately and provide instant relief from pain. At the same time, extended-release tablets take time to work and provide pain relief over time. 

These tablets are available in various strengths such as –

Immediate-Release Tablets –

• 25 mg (generic)
• 50 mg (Ultram, generic)
• 100 mg (generic)

Extended-Release Tablets –

• 100 mg
• 150 mg
• 200 mg
• 300 mg

Oral Solution –

• 5mg/mL
• Equivalent to tramadol 4.4 mg/mL

Use Of Tramadol

Tramadol is usually recommended for the treatment of chronic long-term pain, and it is often used to treat severe and chronic pain. The dose of this medication must be determined by a doctor after an in-depth examination of your health. 

Tramadol is used when non-opioid medications are not sufficient for the treatment and management of pain or are ineffective or easily tolerated. You can safely use this medication on a doctor’s prescription if you are suffering from severe to chronic pain. 

You can take this medication with or without food, but if it upsets your stomach, then you must take it with food. Do not chew or crush the tablets; just swallow them with a glass of water, and you are good to go. 

Talk to your doctor if you are a habitual drinker or if you have any substance use disorder before using this medication to prevent any adverse effects that can be harmful to your health.

Dose Of Tramadol 

The dose may vary from person to person according to age, sex, health conditions, and intensity of pain. 

Extended-release tablets take about 12 to 14 hours to release the formula into the body and dissolve to relieve pain. 

For Acute Pain – 

• The initial recommended dose of this medication for adults is 50 mg – 100 mg, to be taken every 4 to 6 hours. The dose should not exceed more than a maximum of 400 mg in a day. 

For Chronic Non-Cancerous Pain  –

• The initial recommended dose for 18 years or older is 100 mg, to be taken orally once a day. The dose may later be increased for up to 150, 200, or 250 mg after an interval of 5 days. The maximum dosage of this medication to be taken in a day is 300 mg.

Tramadol is not recommended for pediatric patients and to treat cancer pain. People who do not use immediate-release tablets can use extended-release tablets on a doctor’s prescription after evaluating their risks and benefits. 

Side Effects Of Tramadol 

You must take immediate medical attention if you experience any symptoms or side effects while using this medication. Read the instructions given on your prescription list and take the dosage as prescribed by your doctor. 

Some Common Side Effects Of Tramadol Are –

• Dizziness
• Drowsiness
• Tiredness
• Headaches
• Feeling sleepy
• Spaced out 
• Low energy
• Dry mouth
• Sweating 
• Constipation

Some Serious Side Effects Of Tramadol Are – 

• Confusion
• Hallucination
• Low-blood pressure 
• Difficulty in breathing

This medication is not recommended by doctors to be used during pregnancy. Otherwise, it can lead to premature birth of the baby as Tramadol passes through placental barriers. 

Older adults 65 years or older or those who have any kidney or liver problems should take a lower dose of this medication because they have a relatively slower metabolism than younger adults, which lets the medicines stay in the body for longer, leading to severe liver damage. 

You must talk to your doctor if you have any kidney or liver problems before using this medication to prevent any adverse effects of this medication that can prove to be life-threatening to your health. 

Precautions 

To prevent any risk of abuse, misuse, and addiction, and to prevent any severe side effects, you must follow the dosage as prescribed by your doctor and read the instructions given on your prescription list.

• Pregnant women should avoid using this medication to prevent premature birth of the baby. 
• Avoid overdosing or increasing the dose, as it can lead to respiratory depression. 
• Do not use this medication regularly, more often, or for a prolonged period of time to avoid dependency and addiction to it. 
• Tell your doctor, and avoid using Tramadol if you have multiple health issues or severe liver disease. 
• Avoid using Tramadol if you have liver or kidney problems or if you are 65 years or older. 
• Do not take any other opioid medication while using Tramadol. Otherwise, it can lead to severe drug interactions that may prove to be fatal to your health. 
• Children below 12 years of age should not use this medication without consulting a doctor. 

Final Words 

Tramadol contains a higher risk of abuse and misuse, and using this medication on a regular basis for a prolonged period can cause dependency that can lead to addiction. So, you must remember to take the doses as prescribed by your doctor. 

The WHO (World Health Organization) expert committee talked about drug dependence and later concluded that Tramadol has a higher risk of addiction that is similar to opioid medications such as morphine. 

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