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Zolpidem Description 

Zolpidem is a non-benzodiazepine medication, and it is a receptor modulator that is primarily used in the short-term treatment of Insomnia aimed at patients with difficulty falling asleep and staying asleep. 

This medication is classified as a class IV controlled substance, which is regulated by the drug enforcement agency. This medication is recommended to be used for a short-term period because prolonged use can cause dependency, tolerance, and cognitive side effects. 

This medication works by affecting the gamma-aminobutyric acid in the brain to improve sleep and provide relaxation. This medication helps in faster sleep initiation and staying asleep for a longer period of time in a person with Insomnia. 

Other medications in the sedative-hypnotics class include drugs like eszopiclone (Lunesta) and zaleplon (Sonata), which also treat sleep issues but may differ in how quickly they act or how long they last.

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Strength And Forms Of Zolpidem

Zolpidem tablets come in two forms such as immediate-release and extended-release tablets. Immediate-release tablets help a person fall asleep faster, and extended-release tablets help people stay asleep for a longer period of time, providing quality sleep. 

These tablets are available in various strengths such as –

Immediate-Release Tablets – 

  • 5 mg
  • 10 mg

Extended-Release Tablets –

  • 6.25 mg
  • 12.5 mg

Sublingual Tablets –

  • 1.75 mg (Intermezzo)
  • 3.5 mg
  • 5 mg
  • 10 mg

Use Of Zolpidem

Zolpidem is initially used to treat and manage Insomnia, a sleeping condition that makes it difficult for a person to initiate sleep and stay asleep for a longer period of time. It is particularly effective for short-term treatment, especially when someone is struggling with sleep onset.

Those who are suffering from Insomnia caused by anxiety and depression can safely use this medication on a doctor’s prescription. This medication is advised to be taken just before bedtime, as it starts working within 15 – 30 minutes

It is important to maintain a sleeping schedule of about 7 – 8 hours before taking a dose of this medication to avoid feeling groggy or impaired the next day. This medication is recommended for the short-term treatment of about 7 – 10 days

A person should avoid using this medication if they do not have sufficient time to sleep or if they have to wake up in between sleep. Otherwise, it can cause dizziness or drowsiness the next day. 

Dose Of Zolpidem

The dose of Zolpidem may vary from person to person according to their age, sex, and health conditions. It is not recommended to increase or adjust the dose of this medication otherwise, an excess or inadequate dose of this medication may prove to be life-threatening to your health.

Immediate-Release Tablets –

  • The initial recommended dose of an immediate-release tablet is 5 mg for women and 5 – 10 mg for men, to be taken once per night just before bedtime. 
  • For older adults, the dose should be 5 mg to be taken once per night just before bedtime, as they are more sensitive to the effects of sedative-hypnotics. 

Extended-Release Tablets (maintenance dose)-

  • For adults, the usual starting dose is 6.25mg for women and 6.25 – 12.25mg for men, to be taken just before bedtime.
  • For older people, the dose should be 6.25mg, taken just before bedtime, to reduce the risks of side effects. 

Sublingual Tablets –

  • For adults, the dose is typically 1.75mg for women and 3.5mg for men

Side Effects Of Zolpidem

Zolpidem can cause mild to serious side effects that may prove to be fatal to your health. Here is a summary of the most common and notable side effects caused by Zolpidem are –

Some Common Side Effects Of Zolpidem Are – 

  • Dizziness
  • Drowsiness
  • Headache
  • Nausea
  • Fatigue

Talk to your doctor or pharmacists if their advice on how to cope does not help and the side effects do not go away and are still bothering you.

Some More Serious Side Effects Of Zolpidem Are –

  • Confusion
  • Memory problem 
  • Mood changes
  • Sleepwalking 
  • Lack of coordination
  • Unusual behavior 
  • Allergic reactions

Take immediate medical attention if you experience any of the side effects while using this medication. Otherwise, if it is left untreated, it may get worse or cause any serious health issues. 

Precautions

To lower the risk of abuse, misuse, and addiction and to prevent any serious side effects, you must read the instructions given on your prescription list, follow the dosage as prescribed by your doctor or healthcare provider, and remember these points to avoid making any mistakes while using this medication.

  • Avoid using Zolpidem without consulting a doctor if you have Myasthenia gravis or sleep apnea.
  • Do not use Zolpidem if you are suffering from any mental health conditions such as anxiety, panic disorder, or depression.
  • Stop using this medication immediately, if you experience any allergic reaction while using Zolpidem.
  • Consult a doctor, and take a lower dose of this medication if you are 65 years or older than that. 

Final Words

These medications contain a higher risk of abuse, misuse, and addiction, and using this medication without a doctor’s prescription may lead to unintentional overdose that may prove to be life-threatening to one’s health.

In case you forget to take a dose of this medication, you must take it as soon as you remember, but if it’s late, then skip it and avoid increasing or repeating or taking two doses at a time.

Overdose of Zolpidem can result in loss of appetite, and most people use it to stay away from stress and to get a better quality sleep, but it can prove to be fatal to their health. 

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